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rabbit polyclonal antibody against dcx  (Cell Signaling Technology Inc)


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    Cell Signaling Technology Inc rabbit polyclonal antibody against dcx
    Rabbit Polyclonal Antibody Against Dcx, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 995 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/rabbit+polyclonal+antibody+against+dcx/Doublecortin+Antibody/pm30920123-119-33-39
    Average 96 stars, based on 995 article reviews
    rabbit polyclonal antibody against dcx - by Bioz Stars, 2026-10
    96/100 stars

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    Related Articles

    Immunofluorescence:

    Article Title: Doublecortin is expressed in trigeminal motoneurons that innervate the velar musculature of lampreys: considerations on the evolution and development of the trigeminal system
    Article Snippet: Studies in lampreys have revealed interesting aspects of the evolution of the trigeminal system and the jaw.. In the present study, we found a marker that distinguishes subpopulations of trigeminal motoneurons innervating two different kinds of oropharyngeal muscles.. Immunofluorescence with an antibody against doublecortin (DCX; a neuronspecific phosphoprotein) enabled identification of the trigeminal motoneurons that innervate the velar musculature of larval and recently transformed sea lampreys.

    Incubation:

    Article Title: Doublecortin is expressed in trigeminal motoneurons that innervate the velar musculature of lampreys: considerations on the evolution and development of the trigeminal system
    Article Snippet: Studies in lampreys have revealed interesting aspects of the evolution of the trigeminal system and the jaw.. In the present study, we found a marker that distinguishes subpopulations of trigeminal motoneurons innervating two different kinds of oropharyngeal muscles.. Immunofluorescence with an antibody against doublecortin (DCX; a neuronspecific phosphoprotein) enabled identification of the trigeminal motoneurons that innervate the velar musculature of larval and recently transformed sea lampreys.

    Article Title: Spatiotemporal Pattern of Doublecortin Expression in the Retina of the Sea Lamprey
    Article Snippet: .. Sections were incubated with a rabbit polyclonal antibody against DCX (Cell Signalling Technology; code no. 4604; dilution 1:300; immunogen: synthetic peptide [KLH-coupled] corresponding to human DCX), overnight at room temperature. .. A goat anti-rabbit immunoglobulin (Ig) antibody (diluted 1:200; Chemicon, Temecula, CA, USA) coupled to Cy3 was then applied for 1 h. The antibodies were always diluted with TBS containing 15% normal goat serum and 0.2% Triton X-100.

    Article Title: DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.
    Article Snippet: Scope: Glucocorticoid receptor (GR) mediates the nutritional programming of offspring performance.. Maternal folic acid has been shown to regulate hippocampal neurogenesis and affect cognitive function in offspring, yet it remains unclear whether and how GR is involved

    Blocking Assay:

    Article Title: DNA Hypomethylation of GR Promoters is Associated with GR Activation and BDNF/AKT/ERK1/2-Induced Hippocampal Neurogenesis in Mice Derived From Folic-Acid-Supplemented Dams.
    Article Snippet: Scope: Glucocorticoid receptor (GR) mediates the nutritional programming of offspring performance.. Maternal folic acid has been shown to regulate hippocampal neurogenesis and affect cognitive function in offspring, yet it remains unclear whether and how GR is involved



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    rabbit polyclonal antibody against doublecortin dcx  (Biorbyt)
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    Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis <t>(doublecortin</t> <t>(DCX)</t> + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).
    Rabbit Polyclonal Antibody Against Doublecortin Dcx, supplied by Biorbyt, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    rabbit polyclonal antibody against dcx  (Cell Signaling Technology Inc)
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    Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis <t>(doublecortin</t> <t>(DCX)</t> + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).
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    Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis <t>(doublecortin</t> <t>(DCX)</t> + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).
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    Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis <t>(doublecortin</t> <t>(DCX)</t> + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).
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    Image Search Results


    Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis (doublecortin (DCX) + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).

    Journal: ACS chemical neuroscience

    Article Title: Protective Effects of Intranasally Administrated Oxytocin-Loaded Nanoparticles on Pentylenetetrazole-Kindling Epilepsy in Terms of Seizure Severity, Memory, Neurogenesis, and Neuronal Damage.

    doi: 10.1021/acschemneuro.2c00124

    Figure Lengend Snippet: Figure 7. Comparison of neurogenesis and apoptosis in the hippocampus. (a) Neurogenesis (doublecortin (DCX) + cells) was higher in the PTZ + NP-OT group when compared to both Ctrl and PTZ groups (*P < 0.05 and ***P < 0.001). (b) Apoptosis (caspase-3 (C-3)++ cells), on the other hand, was increased in the PTZ group when compared to the Ctrl, Ctrl + OT, and Ctrl + NP-OT groups (*P < 0.05). However, the PTZ + OT group showed an increase in apoptosis when compared to Ctrl + OT and Ctrl + NP-OT groups only (*P < 0.05). The PTZ + NP-OT group showed no significant change in apoptosis levels. (c) Representative microphotographs of both DCX+ and C-3+ cells in hippocampus sections counterstained with Mayer’s hematoxylin. Scale bars represent 20 μm. Statistical analyses were performed using the Kruskal−Wallis H test, followed by Dunn’s comparisons of selected group pairs (Ctrl, n = 6; Ctrl + OT, n = 4; Ctrl + NP-OT, n = 4 and 5 for DCX+ and C-3+, respectively; PTZ, n = 8 and 6 for DCX+ and C-3+, respectively; PTZ + OT, n = 5; PTZ + NP-OT, n = 7 and 6 for DCX+ and C-3+, respectively).

    Article Snippet: A rabbit polyclonal antibody against doublecortin (DCX) (Biorbyt, U.K., Cat# orb457335, RRID: AB_2904159) was used to demonstrate neurogenesis on the subgranular zone of DG, and a rabbit polyclonal antibody against caspase-3 (C-3) (Sigma-Aldrich, MO, Cat# ab3623, RRID: AB_91556) was used to evaluate apoptosis (Table 1).

    Techniques: Comparison